Living a long and fulfilling life has been a human aspiration for centuries. But what truly determines longevity? Genetics, lifestyle, or perhaps something else? Modern research reveals that the key to a longer life lies in a comprehensive approach, with blood tests serving as the primary tool for understanding the body’s condition and addressing risks in a timely manner.

Genes: Not a Verdict, Just a Piece of the Puzzle
Genetics plays a role, but its influence should not be overstated. Studies indicate that only 20–30% of the variability in lifespan is determined by genes. The remaining 70–80% hinges on lifestyle, nutrition, physical activity, and environmental factors. This means that even with less-than-ideal genetic predispositions, one can significantly extend active years through informed health management. But how do you know what needs adjustment? The answer lies in blood—a mirror reflecting the body’s internal state.

Blood as a Marker of Longevity
Centenarians, those who live past 100, exhibit unique blood characteristics. The Swedish AMORIS cohort, which studies biomarkers, found that individuals aged 65 and older who maintain low levels of glucose, creatinine, and uric acid tend to live longer. These markers indicate healthy metabolism, minimal inflammation, and efficient liver and kidney function. In essence, blood serves as a map, revealing which bodily systems are functioning optimally and which require attention.Moreover, blood tests can assess biological age—the actual condition of organs and systems, which may differ significantly from chronological age. For instance, research shows that specific brain-related proteins in individuals with a “younger” biological age reduce the risk of death and Alzheimer’s disease by 40%. Regular blood monitoring thus not only tracks current health but also predicts future risks.

Chronic Inflammation: The Silent Enemy of Longevity
One of the primary factors shortening life is chronic inflammation, which is linked to cardiovascular diseases, diabetes, cancer, and cognitive decline. A simple test for C-reactive protein (CRP) can detect hidden inflammatory processes that erode health over time. Armed with this data, individuals can adjust their lifestyle—through diet, increased physical activity, or targeted therapy—to mitigate risks.

Simple Tests and Cutting-Edge Technologies
Beyond blood tests, other methods can gauge longevity potential. Simple assessments, such as balance, grip strength, or ease of standing from the floor, directly correlate with a longer life. These indicators reflect physical fitness and nervous system health, both critical for active aging.Yet, technology takes this further. Tools like Health Octo, developed by the University of Washington, analyze blood data to predict the risk of organ function decline and mortality with up to 90% accuracy. Such systems enable proactive prevention by identifying the body’s “weak links” long before symptoms arise.

Telomeres and DNA: The Frontier of Longevity
At the cellular level, longevity hinges on telomeres—the protective caps at the ends of chromosomes. As we age, telomeres shorten, accelerating cellular aging. However, the activity of telomerase, an enzyme that helps repair telomeres, and effective DNA repair mechanisms can slow this process. Managing factors that affect telomeres—such as stress, lack of sleep, or poor nutrition—is a critical component of any longevity strategy.

How to Apply This Knowledge?
To live longer and better, a systematic approach is essential:

1. Regularly monitor key blood biomarkers: Glucose, lipids, inflammatory markers, and liver and kidney function indicators provide a comprehensive health overview.
2. Assess biological age: Modern tests reveal how “young” your body truly is, allowing you to address vulnerabilities.
3. Act on the data: Proper nutrition, physical activity, stress management, and timely medical interventions can drastically reduce risks.

Blood: Your Strategic Ally
Blood tests are far more than mere numbers—they are a powerful tool for health management. They offer a window into the body, uncovering hidden threats and enabling action before issues become irreversible. In the era of personalized medicine, with advanced AI solutions like Aima Diagnostics, blood becomes your primary guide to longevity. Regular monitoring, a mindful lifestyle, and the use of cutting-edge technologies are not science fiction but a reality that empowers people to live longer and healthier lives today.


Author: Line Strøm,
Published: August 26, 2025